Call for tenders' details

Title:
Implementation of a Multi-OMICs and Inter-species Workflow to Derive Human Refer...
Contracting authority:
European Food Safety Authority (EFSA)
TED publication date:
28/03/2022
Time limit for receipt of tenders:
15/06/2022
Status:
Closed
Information
OC/EFSA/IDATA/2022/01
Implementation of a Multi-OMICs and Inter-species Workflow to Derive Human Reference Points and Health-based Guidance Values (HBGVs) from Quantitative in Vitro Data
The overarching goal of the project is to define, validate and apply a standardised workflow (experimental and computational) for deriving reliable human reference points and HBGVs using cutting edge in-vitro approaches, namely organ-on-a-chip (OoC) platforms and multiple OMICs endpoints (transcriptomics, metabolomics, epigenomics).
Services
Open procedure
Closed
Checked
All lots
2
Public contract
http://www.efsa.europa.eu/en/procurement/tenders.htm
3250000.00 EUR
73000000
Conditions for participation
As stated in the procurement documents.
Selection criteria as stated in the procurement documents
Selection criteria as stated in the procurement documents
Selection criteria as stated in the procurement documents
Selection criteria as stated in the procurement documents
Milestones
28/03/2022 00:00
15/06/2022 14:30
16/06/2022 14:30
Lots
Lot number Title Description
Lot 1
Implementation of a Multi-OMICs and Inter-species Workflow (Objective 1)
• Objective 1: Implementation of a multi-OMICs and inter-species workflow. In phase one, a set of data-rich substances will be selected (6 to 12 compounds) and used for an extensive toxicological screening based on OoC and multi-OMICs profiling (transcriptomics, epigenomics, metabolomics). Selected substances will include legacy hazards in food/feed and compounds/nutrients with positive health claims (e.g. resveratrol, to be used to verify applicability of OMICs in assessing beneficial dietary effects). The experimental design will be largely based on the procedures established in EU ToxRisk.
Lot 2
Lot 2 – Inference of Chemical Grouping from Processed OMICS Data in CTD (Objective 2)
• Objective 2: Inference of chemical grouping from processed OMICS data in the comparative toxicogenomics database (CTD).
Notices
Reference Notice type Publication date
2022/S 061-159288
Contract notice
28/03/2022 00:00