Call for tenders' details

Title:
Implementation of a Multi-OMICs Workflow to Derive Human Reference Points and He...
Contracting authority:
European Food Safety Authority (EFSA)
TED publication date:
27/02/2023
Time limit for receipt of tenders:
22/05/2023
Status:
Closed
Information
OC/EFSA/IDATA/2023/02
Implementation of a Multi-OMICs Workflow to Derive Human Reference Points and Health-based Guidance Values (HBGVs) from Quantitative in Vitro Data
The overarching goal of the project is to define, validate and apply a standardised workflow (experimental and computational) for deriving reliable human reference points and health-based guidance values (HBGVs) using cutting edge in-vitro approaches, namely organ-on-chip (OoC) platforms and multiple OMICs endpoints (transcriptomics, metabolomics, and epigenomics). The newly generated data will be used to develop and train a bioinformatics pipeline suitable to predict mechanistic information such as mode of action (MoA), adverse outcome pathways (AOP), key biomarkers, in-vivo reference points (using IVIVE-PBK modelling) and health-based guidance values (HBGV).In phase two, the experimental and bioinformatics workflow, defined and tested in phase one, will be used to predict the aforementioned reference points and mechanistic information for a new set of emerging hazardous substances or substances with positive health claims related to food and feed.
Services
Open procedure
Closed
Checked
Public contract
http://www.efsa.europa.eu/en/procurement/tenders.htm
Best price-quality ratio
3,000,000.00 EUR
3,000,000.00 EUR
73000000
ITH52
Conditions for participation
Selection criteria as stated in the procurement documents
Selection criteria as stated in the procurement documents
Selection criteria as stated in the procurement documents
Selection criteria as stated in the procurement documents
Milestones
27/02/2023 00:00
22/05/2023 14:30
23/05/2023 14:30
Lots The call for tenders has no lots.
Notices
Reference Notice type Publication date
2023/S 093-288612
Corrigendum
15/05/2023 00:00
2023/S 041-120969
Contract notice
27/02/2023 00:00