Information

Tender reference number	OC/EFSA/IDATA/2023/02
Title	Implementation of a Multi-OMICs Workflow to Derive Human Reference Points and Health-based Guidance Values (HBGVs) from Quantitative in Vitro Data
Description	The overarching goal of the project is to define, validate and apply a standardised workflow (experimental and computational) for deriving reliable human reference points and health-based guidance values (HBGVs) using cutting edge in-vitro approaches, namely organ-on-chip (OoC) platforms and multiple OMICs endpoints (transcriptomics, metabolomics, and epigenomics). The newly generated data will be used to develop and train a bioinformatics pipeline suitable to predict mechanistic information such as mode of action (MoA), adverse outcome pathways (AOP), key biomarkers, in-vivo reference points (using IVIVE-PBK modelling) and health-based guidance values (HBGV).In phase two, the experimental and bioinformatics workflow, defined and tested in phase one, will be used to predict the aforementioned reference points and mechanistic information for a new set of emerging hazardous substances or substances with positive health claims related to food and feed.
Contract type	Services
Procedure type	Open procedure
Status	Closed
Published on TED
Submission Method	Electronic
Information about a public contract, a framework agreement or a dynamic purchasing system (DPS)	Public contract
Address of the buyer profile: (URL)	http://www.efsa.europa.eu/en/procurement/tenders.htm
Award method	Best price-quality ratio
Estimated total value	3,000,000.00 EUR
Estimated value	3,000,000.00 EUR
Main CPV	73000000
NUTS	ITH52

Conditions for participation

Suitability to pursue the professional activity, including requirements relating to enrolment on professional or trade registers
Economic and financial standing - List and brief description of selection criteria	Selection criteria as stated in the procurement documents
Economic and financial standing- Minimum level(s) of standards possibly required	Selection criteria as stated in the procurement documents
Technical and professional ability - List and brief description of selection criteria	Selection criteria as stated in the procurement documents
Technical and professional ability - Minimum level(s) of standards possibly required	Selection criteria as stated in the procurement documents

Milestones

TED publication date	27/02/2023 00:00
Question deadline	12/05/2023 14:30 UTC+02:00
Answer deadline	16/05/2023 23:59 UTC+02:00
Time limit for receipt of tenders	22/05/2023 14:30 UTC+02:00
Conditions for opening tenders (date)	23/05/2023 14:30 UTC+02:00

Lots

The call for tenders has no lots.

Notices

Reference	Notice type	Publication date
2023/S 093-288612	Corrigendum	15/05/2023 00:00
2023/S 041-120969	Contract notice	27/02/2023 00:00