Call for tenders' details

Title:
Investigating in Silico and in Vitro Tools Supporting the Toxicological Assessme...
Contracting authority:
European Food Safety Authority (EFSA)
TED publication date:
07/07/2021
Time limit for receipt of tenders:
22/09/2021
Status:
Closed
Information
OC/EFSA/GMO/2021/02
Investigating in Silico and in Vitro Tools Supporting the Toxicological Assessment of novel Proteins in Food and Feed Risk Assessment
The aim of this procurement procedure is to conclude two direct contracts for the execution of specific tasks over a clearly defined period, as defined in the tender specifications.Lot 1: Developing in-silico methodologies to predict protein toxicity of novel proteins in the context of food and feed risk assessment;Lot 2: Identifying in vitro toxicity testing approaches for novel proteins in the context of food and feed risk assessment.
Services
Open procedure
Closed
Checked
All lots
2
Public contract
http://www.efsa.europa.eu/en/procurement/tenders.htm
350000.00 EUR
73000000
Conditions for participation
Selection criteria as stated in the procurement documents
Selection criteria as stated in the procurement documents
Selection criteria as stated in the procurement documents
Selection criteria as stated in the procurement documents
Milestones
07/07/2021 00:00
22/09/2021 14:30
23/09/2021 14:30
Lots
Lot number Title Description
Lot 1
Developing in-silico Methodologies to Predict Protein Toxicity of Novel Proteins in the Context of Food and Feed Risk Assessment
To explore methodology/ies to predict the toxicity of a novel protein subject of risk assessment. To identify candidate methodology(ies) for subsequent implementation; the area of proteins newly expressed in GMOs (insecticidal proteins, enzymes conferring resistance to herbicides, proteins intervening on plants metabolic pathways) should be considered.— to propose specific protocols describing the identified methodology(ies); threshold criteria should be identified. Examples of application of the identified protocols will be provided;— to identify strengths, limits and gaps of the proposed methodology/ies.
Lot 2
Identifying in Vitro Toxicity Testing Approaches for Novel Proteins in the Context of Food and Feed Risk Assessment
The objectives of the contract resulting from this procurement procedure are as follows:— to identify, through a comprehensive literature search, available in vitro systems suitable to investigate the toxicity of proteins;— to propose testing strategies for toxic proteins representative of the mechanism/mode of action, biological processes and cellular responses as above described; a fit-for purpose battery of in vitro tools should be defined for each of these;— to identify limitations and gaps of vitro systems in protein toxicity identification in the context of risk assessment;— to identify development needs.
Notices
Reference Notice type Publication date
2021/S 158-417213
Corrigendum
17/08/2021 00:00
2021/S 129-341163
Contract notice
07/07/2021 00:00